Hayashi, Yusuke
Tanabe, Naoya
Sato, Atsuyasu
Hirano, Tsunahiko
Iwamoto, Hiroshi
Maetani, Tomoki
Shiraishi, Yusuke
Sakamoto, Ryo
Sunadome, Hironobu
Fukatsu-Chikumoto, Ayumi
Otani, Toshihito
Higaki, Naoko
Amano, Yoshihiro
Okimoto, Tamio
Yamane, Mayuka
Yokoyama, Akihito
Date, Hiroshi
Sato, Susumu
Hattori, Noboru
Matsunaga, Kazuto
Hirai, Toyohiro
Funding for this research was provided by:
Japan Society for the Promotion of Science (22K08233)
Article History
Received: 13 November 2025
Accepted: 20 April 2026
First Online: 27 April 2026
Declarations
:
: This study was approved by the Ethics Committee of Kyoto University Hospital (No. R2911-3, R4917, R1660-7) in accordance with the Declaration of Helsinki. Written informed consent was obtained from all patients with asthma but waived for healthy controls due to the retrospective design.
: Not applicable.
: Naoya Tanabe and Toyohiro Hirai received research grants from Daiichi Sankyo and Fujifilm Co. Ltd. outside the submitted work. Susumu Sato received grants from Nippon Boehringer Ingelheim, Philips-Respironics, Fukuda Denshi, Fukuda Lifetec Keiji, and ResMed outside of the submitted work. None of these companies played a role in the design or analysis of the study or writing of the manuscript. The remaining authors have no conflicts of interest to declare.