Gowanlock, Sarah N.
Lam, Victor H.K.
Tepe, Zeynep Güneş
Park, Daniel E.
Tai, Vera
Salazar, Juan E.
Pham, Tony
Khan, Yazan
Nelson, Sydney
Horn, Caitlin
Zuanazzi, David
Yang, Diana
Price, Lance B.
Kaul, Rupert
Sowerby, Leigh
Troyer, Ryan M.
Liu, Cindy M.
Prodger, Jessica L.
Funding for this research was provided by:
Canada Institutes of Health Research, Canada Graduate Scholarship Doctoral Award (176586)
National Institute of Allergy and Infectious Diseases, National Institutes of Health (R01AI125562-01)
National Institute of Allergy and Infectious Diseases, National Institutes of Health (R01AI168182-01)
Canada Research Chairs Program (CRC-2020-00175)
Canada Foundation for Innovation (CFI 42343)
Article History
Received: 18 December 2025
Accepted: 22 April 2026
First Online: 14 May 2026
Declarations
Ethics approval and consent to participate: Institutional review boards approved the collection of nasal swabs and tissue specimens, and all volunteers provided written informed consent. Nasal swabs collected from the healthcare worker and George Washington Occupational Health cohorts were approved by the George Washington University Institutional Review Board (IRB# NCR202448 and NCR213697, respectively). Material transfer and data use agreements were approved by the Research Ethics Board of Western University (project ID: 119682), along with approval for the isolation of primary nasal epithelial cells from nasal turbinate tissues (project ID: 119682).
Consent for publication: Not applicable.
Competing interests: CML is a shareholder and a scientific advisor of Trench Therapeutics Inc. The remaining authors declare that they have no competing interests.