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Angiotensin II-induced upregulation of SGLT1 and 2 contributes to human microparticle‐stimulated endothelial senescence and dysfunction: protective effect of gliflozins

Crossref DOI link: https://doi.org/10.1186/s12933-021-01252-3

Published Online: 2021-03-16

Published Print: 2021-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Park, Sin-Hee

Belcastro, Eugenia

Hasan, Hira

Matsushita, Kensuke

Marchandot, Benjamin

Abbas, Malak

Toti, Florence

Auger, Cyril

Jesel, Laurence

Ohlmann, Patrick

Morel, Olivier

Schini-Kerth, Valérie B.
Funding

Funding for this research was provided by:

Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany

Groupe pour l’Enseignement de la Recherche Cardio-vasculaire en Alsace, France
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Article History

Received: 18 January 2021

Accepted: 23 February 2021

First Online: 16 March 2021

Ethics approval and consent to participate

: All animal procedures complied with the Guide of Care and the Use of Laboratory Animals published by the U.S. National Institutes of Health (Bethesda, MD, USA; NIH publication number 85-23, revised 1996), and with the French laws.The procedure was approved by the Local Animal Welfare Committee (SBEA, procedure MAM003).

: Not applicable.

: This work was supported by an unrestricted research grant from Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany.

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