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Authors
Boutari, Chrysoula
Stefanakis, Konstantinos
Simati, Stamatia
Guatibonza-García, Valentina
Valenzuela-Vallejo, Laura
Anastasiou, Ioanna A.
Connelly, Margery A.
Kokkinos, Alexander
Mantzoros, Christos S.
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Clinical Trials BETA
Clinical trials referenced in this document:
nct03986684 at ClinicalTrials.govDocuments that mention this clinical trial
Circulating total and H-specific GDF15 levels are elevated in subjects with MASLD but not in hyperlipidemic but otherwise metabolically healthy subjects with obesity
https://doi.org/10.1186/s12933-024-02264-5
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Article History
Received: 7 April 2024
Accepted: 3 May 2024
First Online: 18 May 2024
Declarations
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: Study 1 was approved by the Institutional and Ethics review boards of Laiko General Hospital, and Study 2 was approved by the Institutional and Ethics review board of Ippokration Hospital. Both studies received exempt status approval by the BIDMC IRB, and conducted in accordance with the Declaration of Helsinki. All participants provided written informed consent. Samples were analyzed blindly at both BIDMC, Boston MA, USA and Ansh Laboratories, Webster, TX in the USA and data were statistically analyzed at BIDMC, Boston MA, USA.
: Not applicable.
: CB, KS, VG, LV-V, SS and IAA have nothing to declare. MAC is an employee of and holds stock in Labcorp. AK has received grants through his institution and consulting fees from Novo Nordisk, Pharmaserve Lilly, Elpen pharmaceuticals, as well as consulting fees from Astra Zeneca, MSD, Sanofi, Bausch Health, Ethicon, Galenica Pharma, and Epsilon Health. None is related to the work presented herein. CSM reports grants through his institution from Merck and Boehringer Ingellheim, grants through his institution and personal consulting fees from Coherus Inc., AltrixBio, and reports personal consulting fees and support with research reagents from Ansh Inc., reports personal consulting fees from Genfit, Lumos, Amgen, Corcept, Intercept, 89Bio, AstraZeneca and Regeneron, reports travel support and fees from TMIOA, Elsevier, College Internationale Research Servier and the Cardio Metabolic Health Conference. None is related to the work presented herein.
