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Genetic variation in the glucagon-like peptide-1 receptor protein encoding region is associated with higher heart rate variability, but not with neurodegeneration of the brain, retina, and peripheral nerves: The Maastricht study

Crossref DOI link: https://doi.org/10.1186/s12933-025-02888-1

Published Online: 2025-10-14

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

van der Heide, Frank C. T.

Steens, Indra L. M.

Singh-Manoux, Archana

Sabia, Séverine

Zhou, Tan Lai

Köhler, Sebastian

Schram, Miranda T.

van der Kallen, Carla J. H.

Berendschot, Tos T. J. M.

Webers, Carroll A. B.

van Greevenbroek, Marleen M. J.

Wesselius, Anke

Arts, Ilja C. W.

Jansen, Jacobus F. A.

Backes, Walter H.

van Sloten, Thomas T.

Blokland, Gabriëlla A. M.

Stehouwer, Coen D. A.
Funding

Funding for this research was provided by:

Dutch Diabetes Foundation (2021.81.004)

European Union (101043884)
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Text and Data Mining valid from 2025-10-14

Version of Record valid from 2025-10-14
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Article History

Received: 25 April 2025

Accepted: 28 July 2025

First Online: 14 October 2025

Declarations

:

: The study was approved by the institutional medical ethical committee (NL31329.068.10) and the Minister of Health, Welfare and Sports of the Netherlands (Permit 131088-105234-PG). All participants gave written informed consent.

: Not applicable.

: The authors declare no competing interests.

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