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Authors
Qu, Kaiyong https://orcid.org/0000-0002-5295-0361
Dal Canto, Elisa
van Ommen, Anne-Mar L. N.
Kamar, Sabrina Abou
Teske, Arco J.
Cramer, Maarten Jan
Verhaar, Marianne C.
Duncker, Dirk J.
Rutten, Frans H.
Kardys, Isabella
Menken, Roxana
Hofstra, Leonard
Tulevski, Igor I.
Somsen, G. Aernout
Onland-Moret, N. Charlotte
Benavente, Ernest Diez
den Ruijter, Hester M.
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Funding
Funding for this research was provided by:
Dutch Cardiovascular Alliance grant (2020B008 RECONNEXT and 2020B004 IMPRESS)
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Article History
Received: 11 August 2025
Accepted: 10 October 2025
First Online: 12 November 2025
Declarations
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: The HELPFul registry received ethical approval from the Medical Ethics Review Committee (METC) of the UMC Utrecht, with METC protocol number 16-290/M-X and CCMO number NL57077.041.16. All study participants provided written informed consent.
: Not applicable.
: I. Kardys received travel reimbursement from SomaLogic. The other authors declare no relevant financial or non-financial relationships with industry in relation to the content of this manuscript.
