Meer, R. https://orcid.org/0000-0002-4924-4458
Hoek, A. G. https://orcid.org/0000-0002-3656-7872
Dal Canto, E. https://orcid.org/0000-0001-8999-9946
Doesburg, T. https://orcid.org/0000-0003-0628-3307
Pasch, A. https://orcid.org/0000-0002-7439-0748
Vervloet, M. G. https://orcid.org/0000-0003-4607-9415
de Jong, P. A. https://orcid.org/0000-0003-4840-6854
Elders, P. J. M. https://orcid.org/0000-0002-5907-7219
Beulens, J. W. J. https://orcid.org/0000-0002-4181-0937
Funding for this research was provided by:
Nederlandse Organisatie voor Wetenschappelijk Onderzoek (91718304)
Article History
Received: 11 August 2025
Accepted: 7 November 2025
First Online: 10 December 2025
Declarations
:
: The Early-HFpEF study was conducted in agreement with the principles of the Declaration of Helsinki and was in accordance with the Medical Research Involving Human Subjects Act (WMO). The study was approved by the Medical Ethical Committee VUmc (METC VUmc, 2018.064—EARLY-HFPEF).
: Not applicable.
: Author AP is inventor of the T 50 test and both stock holder and president of Calciscon (Biel, Switzerland). All other authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.