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Genetically proxied glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide receptor pathway modulation is associated with favorable aging phenotypes: a drug-target Mendelian randomization study

Crossref DOI link: https://doi.org/10.1186/s12933-026-03304-y

Published Online: 2026-07-22

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Li, Jiang

Li, Jie

Xu, Xiaoqin

Wang, Ningjian

Lu, Yingli

Wang, Bin https://orcid.org/0000-0002-4869-1352
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (82404337, 82170870, and 82120108008)
License Information

Text and Data Mining valid from 2026-07-22

Version of Record valid from 2026-08-25
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Article History

Received: 19 April 2026

Accepted: 15 July 2026

First Online: 22 July 2026

Declarations

Ethics approval and consent to participate: Summary-level GWAS statistics used in this study are publicly available and no specific ethical approval was required.

Competing interests: The authors declare no competing interests.

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