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Authors
Won, Ki-Bum
Lee, Byoung Kwon
Hadamitzky, Martin
Kim, Yong-Jin
Sung, Ji Min
Conte, Edoardo
Pontone, Gianluca
Andreini, Daniele
Budoff, Matthew J.
Gottlieb, Ilan
Chun, Eun Ju
Cademartiri, Filippo
Maffei, Erica
Marques, Hugo
de Araújo Gonçalves, Pedro
Leipsic, Jonathon A.
Lee, Sang-Eun
Shin, Sanghoon
Choi, Jung Hyun
Samady, Habib
Chinnaiyan, Kavitha
Narula, Jagat
Shaw, Leslee J.
Bax, Jeroen J.
Min, James K.
Chang, Hyuk-Jae
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Clinical Trials BETA
Clinical trials referenced in this document:
nct02803411 at ClinicalTrials.govDocuments that mention this clinical trial
Coronary artery calcium paradox and physical activity
https://doi.org/10.1136/heartjnl-2021-319868
Rapid Plaque Progression Is Independently Associated With Hyperglycemia and Low HDL Cholesterol in Patients With Stable Coronary Artery Disease: A PARADIGM Study
https://doi.org/10.1161/circimaging.123.016481
Rapid progression of coronary atherosclerosis across glycemic status: a serial coronary computed tomography angiography study from the PARADIGM registry
https://doi.org/10.1186/s12933-026-03355-1
Quantitative assessment of coronary plaque volume change related to triglyceride glucose index: The Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography IMaging (PARADIGM) registry
https://doi.org/10.1186/s12933-020-01081-w
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Funding
Funding for this research was provided by:
Korea Planning & Evaluation Institute of Industrial Technology (RS-2023-00237687)
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Article History
Received: 15 July 2026
Accepted: 22 August 2026
First Online: 5 September 2026
Declarations
Ethics approval and consent to participate: The ethics committee of each participating institution approved the study protocol. Informed consent for the procedure was obtained from all participants.
Consent for publication: Not applicable.
Competing interests: The authors declare the following financial interests and personal relationships that may be considered potential competing interests. Dr. Hyuk-Jae Chang receives funding from the Korea Planning & Evaluation Institute of Industrial Technology (KEIT). Dr. Jonathon Leipsic serves as a consultant to HeartFlow and holds stock options in the company. Dr. James K. Min receives research funding from GE HealthCare and serves on the Scientific Advisory Board of Arineta and GE HealthCare. Dr. Min also is an employee of and holds an equity interest in Cleerly, Inc. The remaining authors declare no competing interests relevant to this work.
