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Combinatorial pathway enzyme engineering and host engineering overcomes pyruvate overflow and enhances overproduction of N-acetylglucosamine in Bacillus subtilis

Crossref DOI link: https://doi.org/10.1186/s12934-018-1049-x

Published Online: 2019-01-04

Published Print: 2019-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Ma, Wenlong

Liu, Yanfeng

Lv, Xueqin

Li, Jianghua

Du, Guocheng

Liu, Long https://orcid.org/0000-0002-9679-9130
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (31622001)

National Natural Science Foundation of China (31671845)

National Natural Science Foundation of China (21676119)

National Natural Science Foundation of China (31600068)

Natural Science Foundation of Jiangsu Province (BK20160176)

Fundamental Research Funds for the Central Universitie (JUSRP11725)

111 Projec (111-2-06)

China Postdoctoral Science Foundation (2016M600363)

China Postdoctoral Science Foundation (2017T100327)

China Postdoctoral Science Foundation (2018M630523)
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Article History

Received: 9 September 2018

Accepted: 24 December 2018

First Online: 4 January 2019

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