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N-alkylisatin-based microtubule destabilizers bind to the colchicine site on tubulin and retain efficacy in drug resistant acute lymphoblastic leukemia cell lines with less in vitro neurotoxicity

Crossref DOI link: https://doi.org/10.1186/s12935-020-01251-6

Published Online: 2020-05-15

Published Print: 2020-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Keenan, Bryce

Finol-Urdaneta, Rocio K.

Hope, Ashleigh

Bremner, John B.

Kavallaris, Maria

Lucena-Agell, Daniel

Oliva, María Ángela

Díaz, Jose Fernando

Vine, Kara L. http://orcid.org/0000-0001-6871-1149
Funding

Funding for this research was provided by:

Horizon 2020 (H2020-MSCA-ITN-ETN/0582 ITN TubInTrain)
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Text and Data Mining valid from 2020-05-15

Version of Record valid from 2020-05-15
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Article History

Received: 25 March 2020

Accepted: 7 May 2020

First Online: 15 May 2020

Ethics approval and consent to participate

: Not Applicable.

: Not Applicable.

: The authors declare there are no competing interests.

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