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Authors
Guo, Rongqi https://orcid.org/0009-0004-9473-6883
Li, Yangyang
Yi, Zhongquan
Zhang, Weisong
Wang, Hao
Wang, Yihao
Li, Xia
Song, Jianxiang
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Funding
Funding for this research was provided by:
Special Research Fund for Clinical Medicine, Nantong University, 2023 (2023JZ022)
2021 Jiangsu Provincial Health and Health Commission Medical Research Guidance Project (Z2021087)
Nantong University’s 2023 Academic Level Research Project (YXY-Z2023008)
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Article History
Received: 21 November 2025
Accepted: 10 February 2026
First Online: 18 February 2026
Declarations
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: The authors declare no competing interests.
: This study was approved by the Ethical Review Committee of the Sixth Hospital Affiliated to Nantong University (Yancheng Third People’s Hospital) (LS-2023-93). Informed consent was obtained from all participants and/or their legal guardians. All animal experiments were conducted in strict accordance with the Regulations on the Management of Laboratory Animals and adhered to the internationally recognized ethical guidelines for the care and use of laboratory animals. The study protocol was reviewed and approved by the Ethics Committee of Jiangsu Medical Vocational College (Approval No.: SYLL-2024-716). All efforts were made to minimize animal suffering and to reduce the number of animals used.
: Written informed consent to participate in this study was obtained from all individual participants (or their legal guardians).
: Written informed consent for publication of anonymized clinical data and any accompanying images was obtained from all individual participants (or their legal guardians).
