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The cancer-testis lncRNA AC007271.3 acts as a decoy of MBP-1 and promotes chemotherapy resistance by inhibiting ferroptosis via c-Myc/GPX4 pathway in oral squamous cell carcinoma

Crossref DOI link: https://doi.org/10.1186/s12935-026-04281-8

Published Online: 2026-03-25

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Qiao, Zihe

Wu, Qingqing

Zhang, Xueni

Wang, Mohan

Zheng, Zenan

Fonseca, Shanoi T.

Lv, Xiaozhi
Funding

Funding for this research was provided by:

Science and Technology Projects in Guangzhou (2024A04J4873)

President Foundation of Zhujiang Hospital,Southern Medical University (yzjj2024qn43)

National Natural Science Foundation of China-Guangdong Joint Fund (2024A1515013010)
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Text and Data Mining valid from 2026-03-25

Version of Record valid from 2026-05-04
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Article History

Received: 31 January 2026

Accepted: 18 March 2026

First Online: 25 March 2026

Declarations

:

: The authors affirm that all methods were conducted in accordance with the relevant guidelines and regulations. All mice were housed at the Animal Center of Southern Medical University, and approval was obtained from the Animal Committee of the Institute of Zoology at Southern Medical University (reference number: L2018199, LAEC-2025-053). All procedures were performed in accordance with the NIH Guide for the Care and Use of Laboratory Animals. The reporting of this in vivo research adheres to the ARRIVE guidelines 2.0.

: The authors declare no competing interests.

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