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Effects of Spirulina (Arthrospira) platensis supplementation on intestinal permeability, antioxidant and inflammatory markers, quality of life and disease severity in patients with constipated-predominant irritable bowel syndrome: a randomized double‑blind, placebo‑controlled trial

Crossref DOI link: https://doi.org/10.1186/s12937-025-01132-6

Published Online: 2025-04-21

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Nasab, Saeede Jafari

Feizi, Awat

Hajihashemi, Parisa

Entezari, Mohammad-Hassan

Sharma, Manoj

Adibi, Peyman

Bagherniya, Mohammad
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Text and Data Mining valid from 2025-04-21

Version of Record valid from 2025-04-21
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Article History

Received: 5 December 2024

Accepted: 12 April 2025

First Online: 21 April 2025

Declarations

:

: All study protocols were carried out according to the Declaration of Helsinki. All patients provided written informed consent before participation in the trial. The study protocol was approved by the ethical committee at the Isfahan University of Medical Sciences (Registration No. IR.MUI.RESEARCH.REC.1401.370) and registered online at (code: IRCT20140208016529N8, approved date 25.04.2023).

: All authors approved the final version of the manuscript, and agreed for all aspects of the work to be published.

: The authors declare no competing interests.

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