Lai, Jun S.
Lim, Shan Xuan
Barton, Sheila J.
Tham, Elizabeth Huiwen
El-Heis, Sarah
Albert, Benjamin B.
Childs, Caroline E.
Conlon, Cathryn A.
Colega, Marjorelee T.
Cox, Vanessa
Nield, Heidi
Loy, See Ling
Cutfield, Wayne S.
Chong, Mary F.-F.
Godfrey, Keith M.
Chan, Shiao-Yng
Funding for this research was provided by:
National Medical Research Council (MOH-001537-01)
National Medical Research Council (NMRC/TCR/012-NUHS/2014)
Gravida New Zealand Government Centre of Research Excellence
Medical Research Council (MC_UU_12011/4)
National Institute for Social Care and Health Research
National Institute for Health and Care Research (NF-SI-0515-10042; 17/63/154; IS-BRC-1215-20004)
British Heart Foundation (RG/15/17/3174)
European Union (Erasmus+ Programme ImpENSA 598488-EPP-1-2018-1-DE-EPPKA2-CBHE-JP)
National University of Singapore
Agency for Science, Technology and Research (H22P0M0008; H17/01/a0/005)
Article History
Received: 5 October 2025
Accepted: 12 January 2026
First Online: 23 January 2026
Declarations
:
: All procedures in NiPPeR were approved by Research Ethics Committees at each study site [Southampton, UK: Health Research Authority, National Research Ethics Service Committee, South Central Research Ethics Committee (15/SC/0142); Singapore: National Healthcare Group Domain Specific Review Board (2015/00205); Auckland, NZ: Health and Disability Ethics Committee (15/NTA/21)], and conducted according to the Declaration of Helsinki for Medical Research. Informed written consent was obtained from all NiPPeR participants at recruitment.
: Not applicable.
: SYC, WSC and KMG are part of an academic consortium that report grants from Société Des Produits Nestlé S.A. during the conduct of the study and are co-inventors on patent filings by Nestlé S.A. relating to the NiPPeR intervention or its components. SYC has received reimbursement and honoraria into her research funds from Nestlé Nutrition Institute and EGOI (Experts Group on Inositols) for speaking at conferences. KMG has received reimbursement for speaking at conferences sponsored by companies selling nutritional products. All other authors declare no competing interests.