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Article History

Received: 19 July 2018

Accepted: 11 October 2018

First Online: 20 October 2018

Ethics approval and consent to participate

: Animal experiments were carried out in accordance with the guidelines of the institutional animal care and use committee (ARF-SBS/NIE-A0250AZ, −A0324 and -A0321) of Nanyang Technological University, Singapore.

: All authors have read and approved the final manuscript, and consent to publish.

: The authors declare that they have no competing interests.

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