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Remodeling of the tumor microenvironment via disrupting Blimp1+ effector Treg activity augments response to anti-PD-1 blockade

Published Online: 2021-11-20

Published Print: 2021-12

Authors

Dixon, Michael L.

Luo, Lin

Ghosh, Sadashib

Grimes, Jeffrey M.

Leavenworth, Jonathan D.

Leavenworth, Jianmei W. https://orcid.org/0000-0002-4100-9883
Funding

Funding for this research was provided by:

National Institute of Allergy and Infectious Diseases (R01AI148711, T32AI007051)

u.s. department of defense (W81XWH-18-1-0315)

school of medicine, university of alabama at birmingham (Faculty Start-up Funds)

National Institute of Dental and Craniofacial Research (T90DE022736)
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Text and Data Mining valid from 2021-11-20

Version of Record valid from 2021-11-20
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Article History

Received: 13 July 2021

Accepted: 27 October 2021

First Online: 20 November 2021

Declarations

:

: All animal experiments were performed in compliance with federal laws and institutional guidelines as approved by the UAB IACUC. Approval from the UAB Institutional Review Board for Not Human Subjects Research (IRB-300003295) was used for study of melanoma patient samples.

: Not applicable.

: The authors have declared that no conflict of interests exists.

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