Zuckermann, Marc
He, Chen
Andrews, Jared
Bagchi, Aditi
Sloan-Henry, Roketa
Bianski, Brandon
Xie, Jia
Wang, Yingzhe
Twarog, Nathaniel
Onar-Thomas, Arzu
Ernst, Kati J.
Yang, Lei
Li, Yong
Zhu, Xiaoyan
Ocasio, Jennifer K.
Budd, Kaitlin M.
Dalton, James
Li, Xiaoyu
Chepyala, Divyabharathi
Zhang, Junyuan
Xu, Ke
Hover, Laura
Roach, Jordan T.
Chan, Kenneth Chun-Ho
Hofmann, Nina
McKinnon, Peter J.
Pfister, Stefan M.
Shelat, Anang A.
Rankovic, Zoran
Freeman, Burgess B. III
Chiang, Jason
Jones, David T. W.
Tinkle, Christopher L.
Baker, Suzanne J.
Funding for this research was provided by:
Deutscher Akademischer Austauschdienst
National Cancer Institute (CA096832, CA271570, CA21765, CA096832, CA271570, CA21765, CA096832, CA271570, CA21765, CA096832, CA271570, CA21765, CA096832, CA271570, CA21765, CA265285)
National Brain Tumor Society (Defeat Pediatric Brain Tumors, Defeat Pediatric Brain Tumors, Defeat Pediatric Brain Tumors, Defeat Pediatric Brain Tumors, Defeat Pediatric Brain Tumors)
Bundesministerium für Bildung und Forschung (TRANSCAN-2_ project TORPEDO_ 01KT1605)
American Lebanese Syrian Associated Charities
Musicians Against Childhood Cancer, USA
Article History
Received: 4 November 2023
Accepted: 21 May 2024
First Online: 7 June 2024
Declarations
:
: The research performed in this study complies with all relevant ethical regulations. Patient data are from patients treated on clinical protocol SJYC07 or standard institutional protocols. SJYC07 was approved by the institutional review board (IRB # Pro00000332) with written informed consent obtained from patients and families. This trial is registered at clinicaltrials.gov, NCT00602667, and was permanently closed to accrual in April 2017. The IRB approved the review of non-protocol patients with a waiver for consent (IRB# 21-0805). Human tissue samples were procured following informed consent, and all experimental procedures were approved by the Research Ethics Board. Samples of human tumors were directly obtained from the St. Jude Children’s Research Hospital Biorepository.All mouse experiments were performed according to animal welfare regulations and were approved by the Institutional Animal Care and Use Committee (IACUC) at St. Jude Children’s Research Hospital (Protocol 278) or the German Cancer Center (DKFZ) Regierungspräsidium Karlsruhe, approval number G-168/17.
: The authors declare no competing interests.