Boot, Gina F. https://orcid.org/0000-0002-2463-6412
Haak, Fabian https://orcid.org/0000-0002-0279-1745
Coto-Llerena, Mairene https://orcid.org/0000-0001-7596-1250
Boldanova, Tuyana https://orcid.org/0009-0005-2745-0057
Dazert, Eva https://orcid.org/0000-0002-7292-2261
Sedlaczek, Philip https://orcid.org/0000-0002-7310-7103
Rosenberger, George https://orcid.org/0000-0002-1655-6789
Esposito, Cinzia https://orcid.org/0009-0007-8211-0885
Ercan, Caner https://orcid.org/0000-0002-5611-2699
Wieland, Stefan https://orcid.org/0000-0002-4444-977X
Renne, Salvatore Lorenzo https://orcid.org/0000-0002-0186-1318
Benjak, Andrej https://orcid.org/0000-0003-4522-6575
Matter, Matthias S. https://orcid.org/0000-0002-2005-5266
Di Tommaso, Luca https://orcid.org/0000-0002-9013-4728
Hall, Michael N. https://orcid.org/0000-0002-2998-0757
Terracciano, Luigi M. https://orcid.org/0000-0002-9393-9660
Heim, Markus H. https://orcid.org/0000-0002-7523-4894
Piscuoglio, Salvatore https://orcid.org/0000-0003-2686-2939
Ng, Charlotte K. Y. https://orcid.org/0000-0002-6100-0026
Funding for this research was provided by:
Fondazione AIRC per la ricerca sul cancro ETS
European Research Council
NextGenerationEU
Article History
Received: 17 October 2025
Accepted: 2 February 2026
First Online: 6 March 2026
Declarations
:
: Written informed consent was obtained from all patients to use additional biopsy material from diagnostic procedures for research purposes. The study was approved by the ethics committee of the northwestern part of Switzerland (EKNZ 2014–099).
: Not applicable.
: MS M has served as a consultant for ThermoFisher, Merck, GlaxoSmithKline, Janssen-Cilag, Hoffmann–La Roche, and Novartis; received speaker’s honorary from Incyte Biosciences, Merini Group and Astellas, and maintains non-commercial research agreements with AstraZeneca.