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Authors
Chang, Ya-Hsuan
Chen, Yi-Ju
Hong, Zhi-Jie
Hsiao, Yi-Jing
Lin, Kuen-Tyng
Liao, Guo-Shiou
Su, Sheng-Fang
Lin, Ze-Shiang
Chen, Huei-Wen
Han, Chia-Li
Chen, Eric Sheng-Wen
Hsu, Yin-Chen
Chen, Yan-Ming
Fang, Hao
Yang, Hao-Chin
Chen, Yan-Si
Lin, Chien-Yu
Hsu, Hsiang-En
Lin, Ching-Hung
Jiang, Pin-Lian
Wu, Pei-Shan
Chen, Ching-Wen
Hung, Chen-Ting
Wu, Ethan
Chiu, Wei-Tzu
Hsing, Fan-Ni
Liu, Tsai-Pei
Wang, Chia-Yu
Wang, Yu-Tai
Yeh, Chang-Wei
Liao, Ki-Hok
Robles, Ana I
Rodriguez, Henry
Yang, Show-Ling
Hung, Mien-Chie
Lu, Yen-Shen
Chen, Hsuan-Yu
Yu, Sung-Liang
Yu, Jyh-Cherng
Chen, Yu-Ju
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Funding
Funding for this research was provided by:
National Center for High-performance Computing (NCHC) of National Institutes of Applied Research (NIAR) and National Core Facility for Biopharmaceuticals (NCFB 111-2740-B-492-001; NCFB, NSTC 114-2740-B-492-001)
National Core Facility for Biopharmaceuticals Pharmacogenomics Lab TR6 (MOST 111-2740-B-002-005)
Tri-Service General Hospital (MOST 105-2314-B-016-041-MY3, MOST 107-2314-B-016-025, and TSGH-C108-126)
Key and Novel Therapeutics Development Program for Major Diseases (AS-KPQ-111-KNT)
Medicinal Chemistry and Analytical Core Facilities (AS-NBRPCF-111-201)
Next-Generation Pathway of Taiwan Cancer Precision Medicine Program (AS-KPQ-107-TCPMP)
Academia Sinica Common Mass Spectrometry Facilities (AS-CFII-111-209)
Intelligent Multi-Omics Precision Medicine (AS-KPQ-115-IMPM)
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Article History
Received: 6 November 2025
Accepted: 27 May 2026
First Online: 3 June 2026
Declarations
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: All participants provided written informed consent in accordance with institutional guidelines and the Declaration of Helsinki. All procedures were approved by the institutional research ethics committees (Application No.: AS-IRB-BM-17056 and 1-106-05-168).
: The authors declare no competing interests.
