Sikora Kessler, Asia https://orcid.org/0000-0001-9417-6637
Baum, Seth J.
Kutrieb, Emily
Vera Llonch, Montserrat
Lonshteyn, Alex
Weycker, Derek https://orcid.org/0000-0002-5405-2215
Soffer, Daniel E.
Funding for this research was provided by:
Ionis Pharmaceuticals
Article History
Received: 15 May 2025
Accepted: 30 June 2025
First Online: 28 July 2025
Change Date: 1 March 2026
Change Type: Update
Change Details: The original online version of this article was revised: typesetting error in table 1 was updated accordingly.
Change Date: 3 March 2026
Change Type: Correction
Change Details: A Correction to this paper has been published:
Change Details: https://doi.org/10.1186/s12944-026-02898-2
Declarations
:
: The study data sources were de-identified prior to their release to study investigators, as set forth in the corresponding Data Use Agreement. Use of the study data sources for health services research was fully compliant with the Health Insurance Portability and Accountability Act (HIPAA) Privacy Rule and federal guidance on Public Welfare and the Protection of Human Subjects (45 CFR 46 ยง46.101); accordingly, Institutional Review Board (IRB) approval was not required.
: All authors agree to publish this article in the Journal of Lipids in Health and Disease.
: Alex Lonshteyn and Derek Weycker are employed by Avalere Health. Emily Kutrieb was employed by Avalere Health during the design and conduct of this study. Daniel E. Soffer is employed by the University of Pennsylvania Health System, and Seth J. Baum is employed by Flourish Research. Asia Sikora Kessler and Montserrat Vera Llonch are employed by Ionis Pharmaceuticals. Daniel E. Soffer reports the following relationships with Industry - Consultant/Advisor: Amgen Inc, Amryt, Endless Health, GenInCode, Heartflow, Ionis, New Amsterdam, PHAR, Regeneron; and receives institutional support as sub-investigator in clinical trials with: Akcea, Amgen, Amryt, Arrowhead, Ionis, Lilly, Novartis, PCORI, NIH, Heartflow.