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Explainable machine learning-driven models for predicting Parkinson’s disease and its prognosis: obesity patterns associations and models development using NHANES 1999–2018 data

Crossref DOI link: https://doi.org/10.1186/s12944-025-02664-w

Published Online: 2025-07-17

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Fan, Jiaxin

Cao, Shuai

Peng, Hang

Zhi, Yuanjie

Zhan, Shuqin

Li, Rui
Funding

Funding for this research was provided by:

Natural Science Basic Research Project in Shaanxi Province (2024JC-YBQN-0861)

Key Innovation Cluster in Social Health Development Project in Shaanxi Province (2022ZDLSF04-06)
License Information

Text and Data Mining valid from 2025-07-17

Version of Record valid from 2025-07-17
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Article History

Received: 13 May 2025

Accepted: 6 July 2025

First Online: 17 July 2025

Declarations

:

: The NCHS Ethics Review Board evaluated and granted approval for the NHANES survey (), and informed consent was obtained from all participants at the time of NHANES enrollment. Due to the nature of open access and the deidentification of data, this study was exempt from ethical approval by the Ethics Committee of Shaanxi Provincial People’s Hospital.

: All authors have read, validate the accuracy of the data and approved the final manuscript.

: The authors declare no competing interests.

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