Li, Han
Wang, Yunqiao
Zheng, Wei
Lu, Jing
Tang, Cuiyao
Long, Mengyang
Liu, Bo
Chen, Bin
Li, Weihong
Xu, Zihui
Funding for this research was provided by:
Youth Doctoral Incubation Program of the Second Affiliated Hospital of Army Medical University (2023YQB030, 2024YQB007)
Chongqing Yingcai Master and Teacher Programme (CQYC20220203145)
Chongqing Bayu Qihuang Scholars Support Programme
Article History
Received: 17 April 2025
Accepted: 25 August 2025
First Online: 8 October 2025
Declarations
:
: All animal experimental procedures in this study were conducted in strict accordance with the National Research Council (NRC) Guide for the Care and Use of Laboratory Animals(2011), the 3Rs Principles(Replacement, Reduction, Refinement) endorsed by the NC3Rs (National Centre for the Replacement, Refinement & Reduction of Animals in Research), and the American Veterinary Medical Association (AVMA) Guidelines for the Euthanasia of Animals(2020). The study protocol, including animal welfare measures, experimental design, and euthanasia endpoints, was reviewed and approved by the Laboratory Animal Welfare and Ethics Committee of the Army Medical University, with approval number AMUWEC20245307, obtained on January 20, 2025.
: The authors declare no competing interests.