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4-phenylbutyric acid attenuates hepatic ER stress, pyroptosis, and NAFLD in adult rat offspring exposed to a high-fat, high-fructose diet during perinatal and adulthood

Crossref DOI link: https://doi.org/10.1186/s12944-026-02882-w

Published Online: 2026-02-24

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Ojaghi, Sara

Eskandari, Farzaneh

Azarkish, Fariba

Soltani, Haniyeh

Binayi, Fateme

Saeidi, Behnam

Hedayati, Mehdi

Goudarzi, Afsaneh

Amini, Abdollah

khodagholi, Fariba

Zardooz, Homeira
Funding

Funding for this research was provided by:

Shahid Beheshti University of Medical Sciences (43008299)
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Text and Data Mining valid from 2026-02-24

Version of Record valid from 2026-03-30
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Article History

Received: 22 September 2025

Accepted: 26 January 2026

First Online: 24 February 2026

Declarations

:

: All animal studies complied with the standards set by the Animal Ethics Committee of Shahid Beheshti University of Medical Sciences (IR.SBMU.AEC.1402.097).

: Not applicable in this section.

: The authors declare no competing interests.

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