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Src kinase inhibition with dasatinib impairs neutrophil function and clearance of Escherichia coli infection in a murine model of acute lung injury

Published Online: 2020-10-30

Published Print: 2020-12

Authors

Macfarlane, James G. https://orcid.org/0000-0003-2636-4526
Dorward, David A.

Ruchaud-Sparagano, Marie-Hélène

Scott, Jonathan

Lucas, Christopher D.

Rossi, Adriano G.

Simpson, A. John
Funding

Funding for this research was provided by:

Wellcome Trust (WT095157, WT096497, WT094415)

Medical Research Council (MR/K013386/1)
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Text and Data Mining valid from 2020-10-30

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Article History

Received: 11 June 2020

Accepted: 30 September 2020

First Online: 30 October 2020

Ethics approval and consent to participate

: All in vivo experiments were performed in accordance with UK Home Office regulations (project licence number PPL 60–4531). Approval to obtain whole blood from healthy volunteers was provided by the Newcastle and North Tyneside Research Ethics Committee (reference number 12/NE/0121).

: Not applicable.

: The authors declare that they have no competing interests.

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