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Lipopolysaccharide pretreatment increases the sensitivity of the TRPV1 channel and promotes an anti-inflammatory phenotype of capsaicin-activated macrophages

Crossref DOI link: https://doi.org/10.1186/s12950-024-00391-0

Published Online: 2024-05-24

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Vašek, Daniel

Fikarová, Natálie

Marková, Vendula Nagy

Honc, Ondřej

Pacáková, Lenka

Porubská, Bianka

Somova, Veronika

Novotný, Jiří

Melkes, Barbora

Krulová, Magdaléna
Funding

Funding for this research was provided by:

Grant Schemes at CU (CZ.02.2.69/0.0/0.0/19_073/0016935)

Vinicna Microscopy Core Facility co-financed by the Czech-BioImaging large RI project (LM2023050)

Ministry of Education of the Czech Republic (CZ.02.1.01/0.0/0.0/16_019/0000759)

UNCE (204072)
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Article History

Received: 21 August 2023

Accepted: 7 May 2024

First Online: 24 May 2024

Declarations

:

: This study was carried out in strict accordance with the Act No. 246/1992 coll., on the protection of animals against cruelty, the basic law related to animal protection governing the activities of all the state authorities of animal protection in the Czech Republic. This study protocol was reviewed and approved by The expert commission for ensuring the welfare of experimental animals, Faculty of Science, Charles University approval number MSMT-31167/2021-4.

: Not applicable.

: The authors declare no competing interests.

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