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Carbonic anhydrase IX-targeted H-APBC nanosystem combined with phototherapy facilitates the efficacy of PI3K/mTOR inhibitor and resists HIF-1α-dependent tumor hypoxia adaptation

Crossref DOI link: https://doi.org/10.1186/s12951-022-01394-w

Published Online: 2022-04-12

Published Print: 2022-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Liu, Jie

Hu, Xiaochun

Feng, Lei

Lin, Yun

Liang, Shujing

Zhu, Zhounan

Shi, Shuo https://orcid.org/0000-0003-4387-3445
Dong, Chunyan
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (82073387, 21877084, 81860547, 81703075, 81902999, 81860547, 21671150)

Fundamental Research Funds for the Central Universities (KX0150720173382)

China Postdoctoral Science Foundation Special Funded Project (2020T130476)
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Text and Data Mining valid from 2022-04-12

Version of Record valid from 2022-04-12
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Article History

Received: 9 January 2022

Accepted: 23 March 2022

First Online: 12 April 2022

Declarations

:

: All animal experiments were carried out with full authorization approved by the ethical committee for animal care of School of Medicine, Tongji University (Approval No. TJBB00721103).

: All authors agree to be published.

: The authors declare no competing interest.

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