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Sirtuin-3 activation by honokiol attenuated anesthesia/surgery-induced cognitive impairment and neuronal ferroptosis via inhibiting mitochondrial GPX4 acetylation

Crossref DOI link: https://doi.org/10.1186/s12951-025-03502-y

Published Online: 2025-06-04

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Zeng, Lian

Hu, Pengchao

Wang, Xuan

Ding, Xudong

Wang, Qingsong

Luo, Li

Zhang, Yu

Li, Mingyue

Zhao, Yilin

Li, Shiyong

Luo, Ailin
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (82371208)
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Text and Data Mining valid from 2025-06-04

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Article History

Received: 5 February 2025

Accepted: 27 May 2025

First Online: 4 June 2025

Declarations

:

: The experimental procedures adhered to the “Guide for the Care and Use of Laboratory Animals” published by the National Institutes of Health (NIH) and were approved by the Animal Care and Use Committee of Xiangyang No. 1 People’s Hospital (Ethics Approval No.XYYYE20220047).

: Consent for publication was obtained from the participants.

: The authors declare no competing interests.

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