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Targeting ferroptosis to rescue osteogenic differentiation in BRONJ-affected jawbone mesenchymal stem cells: the role of miR-145-3p and exosome-mediated therapy

Crossref DOI link: https://doi.org/10.1186/s12951-025-03745-9

Published Online: 2025-10-10

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Shuai, Yi

Chen, Bo

Jiang, Tao

Zhu, Lei

Su, Han

Wei, Wei

Liu, Bingyao

Jin, Lei
Funding

Funding for this research was provided by:

Natural Science Foundation of China (82100985, 82071094)

Project of Eastern Theater Command General Hospital (22LCZLXJS12)

China Postdoctoral Science Foundation (2021M693954, 2021T140785)

Nanjing Postdoctoral Research Funding Program (NingRenSheHan[2021]183)

The General Research Project of Nanjing City (YKK24266)

Taikang Health Industry Investment Youth Medical Research Start-up Funding Program (2023008)
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Text and Data Mining valid from 2025-10-10

Version of Record valid from 2025-10-10
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Article History

Received: 15 March 2025

Accepted: 24 September 2025

First Online: 10 October 2025

Declarations

:

: All animal experimental protocols were reviewed and approved by the Department of Comparative Medicine at Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University (Permit No. 2021DZGKJDWLS-0090), strictly adhering to the guidelines set forth by the NIH for the Care and Use of Laboratory Animals.

: Not applicable.

: The authors declare no competing interests.

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