Yin, Shoucheng https://orcid.org/0000-0002-8320-2526
Qiao, Qihui https://orcid.org/0000-0001-6276-0468
Li, Zhaorong
Lu, Lijie
Jiang, Muzhou
Gao, Hanyu
Ge, Ziming
Li, Chen
Pan, Yaping https://orcid.org/0000-0001-6711-8992
Funding for this research was provided by:
Natural Science Foundation of Liaoning Province (2025-BSLH-412)
National Natural Science Foundation of China (82401130)
National Natural Science Foundation of China (82571104)
National Key R&D Program of China (2023YFC2506302)
Liaoning Province “Xingliao Talent Plan” Medical Master Project (XLYC2412038)
Article History
Received: 13 June 2025
Accepted: 29 December 2025
First Online: 9 January 2026
Declarations
:
: The above study with human was conducted in accordance with the Declaration of Helsinki Declaration and corresponding laws and regulations, and was approved by the Medical Ethics Committee of Hospital of Stomatology, China Medical University (approval number: K2023013). All subjects gave full informed consent and signed informed the consent forms. All animal studies complied with the ethical guidelines for researchers by the International Council for Laboratory Animal Science (ICLAS) and were approved by the Committee on Ethics Committee of China Medical University (approval number: CMU20241680).
: Each author approved the manuscript before submission for publication.
: The authors declare no competing interests.