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CD93-targeted resveratrol-loaded PLGA nanoparticles remodel CD8⁺ T cell metabolism through AIF-mediated oxidative phosphorylation to overcome lung cancer immunotherapy resistance

Crossref DOI link: https://doi.org/10.1186/s12951-026-04216-5

Published Online: 2026-03-14

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Jiang, Zhou

Li, Yuning
Funding

Funding for this research was provided by:

the Hunan Provincial Natural Science Foundation (No. 2023JJ40406)

the Hunan Provincial Natural Science Foundation (No. 2023JJ40406)
License Information

Text and Data Mining valid from 2026-03-14

Version of Record valid from 2026-04-23
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Article History

Received: 20 August 2025

Accepted: 12 February 2026

First Online: 14 March 2026

Declarations

:

: All animal experiments were approved by the Animal Ethics Committee of Affiliated Cancer Hospital of Xiangya School of Medicine (No. 2025 − 104). Not applicable.

: Not applicable.

: The authors declare no competing interests.

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