Crossmark

PET-microplastics trigger endothelial glycocalyx loss via ER stress and ROS unleashing IL-1β-driven SMC switching and early aortic structural impairment

Crossref DOI link: https://doi.org/10.1186/s12951-026-04252-1

Published Online: 2026-03-11

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Huo, Weixue

Qu, Jin

Wang, Sen

He, Mengwei

Zeng, Zhaoxiang

Kong, Deping

Yuan, Lushun

Feng, Rui
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (82400835)

National Natural Science Foundation of China (82270505)

Shanghai Pujiang Programme (24PJD090)

Joint Research Project for Emerging Frontier Technologies of Shanghai Shenkang Hospital Development Center (SHDC12022107)
License Information

Text and Data Mining valid from 2026-03-11

Version of Record valid from 2026-04-20
More Information

Article History

Received: 3 October 2025

Accepted: 26 February 2026

First Online: 11 March 2026

Declarations

:

: Ethical approval for this research was granted by the Clinical Research Ethics Committee of Shanghai General Hospital (YLK2023387) and all animal procedures received approval from the Shanghai General Hospital’s Clinical Center Laboratory Animal Welfare & Ethics Committee (2024AW074).

: All authors gave their consent for publication.

: The authors declare no competing interests.

Document is current

Any future updates will be listed below