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Taurine-loaded extracellular vesicles suppress mtDNA–cGAS–STING signaling by enhancing SIRT1-dependent mitophagy to alleviate neuronal senescence after spinal cord injury

Crossref DOI link: https://doi.org/10.1186/s12951-026-05038-1

Published Online: 2026-09-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Liu, Dingming

Yang, Yongkang

zhang, Buzheng

Zhang, Ying

Chen, Yansong

Xu, Yinyang

Zhang, Yanle

Chen, Hongtao

Cao, Xiaojian https://orcid.org/0000-0001-5567-0536
Wu, Chaoqin
Funding

Funding for this research was provided by:

Natural Science Foundation of Jiangsu Province - Youth Fund Project of Basic Research Program (BK20240240)

Original Exploration Project of the National Natural Science Foundation of China (82350002)
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Text and Data Mining valid from 2026-09-12

Accepted Manuscript valid from 2026-09-12
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Article History

Received: 30 April 2026

Accepted: 3 September 2026

First Online: 12 September 2026

Declarations

Ethics approval: All animal experiments were approved by the Ethics Committee of Nanjing Medical University and were conducted in accordance with institutional guidelines for the care and use of laboratory animals.

Competing interests: The authors declare no competing interests.

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