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Authors
Li, Xinyi
Ma, Xuedi
Shi, Changcheng
Qin, Wangjun
Wu, Yibo
Liu, Lihong
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Funding
Funding for this research was provided by:
The CAMS Innovation Fund for Medical Sciences (2024-I2M-C&T-B-092)
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Article History
Received: 25 August 2025
Accepted: 20 January 2026
First Online: 31 January 2026
Declarations
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: This study strictly adhered to the ethical principles outlined in the Declaration of Helsinki for medical research involving human subjects. This study (SWYX: NO.2023-198) has been approved by the Ethics Research Committee of Shandong Provincial Hospital. This study was filed in the National Health Security Information Platform (Record No.: MR‐37‐23‐017876) and officially registered in the China Clinical Trials Registry (Registration No.: ChiCTR2300072573).
: Informed consent was obtained from all individual participants included in the study.
: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
: The authors declare no competing interests.
