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Hypoalbuminemia and hypercalcemia are independently associated with poor treatment outcomes of anti-PD-1 immune checkpoint inhibitors in patients with recurrent or metastatic head and neck squamous cell carcinoma

Crossref DOI link: https://doi.org/10.1186/s12957-024-03522-2

Published Online: 2024-09-11

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Chiu, Tai-Jan

Huang, Tai-Lin

Chien, Chih-Yen

Huang, Wan-Ting

Li, Shau-Hsuan
Funding

Funding for this research was provided by:

Chang Gung Memorial Hospital (CMRPG8N0802 and CORPG8M0461, CMRPG8N0802 and CORPG8M0461)

National Science Council, Taiwan (NSTC 112-2314-B-182A-029-MY3)
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Text and Data Mining valid from 2024-09-11

Version of Record valid from 2024-09-11
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Article History

Received: 26 May 2024

Accepted: 1 September 2024

First Online: 11 September 2024

Declarations

:

: Ethical approval for this study was obtained from the Chang Gung Medical Foundation Institutional Review Board (202200507B0 and 202201019B0). All procedures used in studies involving human participants were performed in accordance with the ethical standards of the Institutional Research Committee and the World Medical Association Declaration of Helsinki. The requirement for written informed consent was waived by the Institutional Review Board of the Chang Gung Medical Foundation .

: Not applicable.

: None.

: The authors declare no competing interests.

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