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Article History

Received: 23 October 2018

Accepted: 3 January 2019

First Online: 10 January 2019

Ethics approval

: All protocols for the study were approved by the Committee for Animal Research of Tor Vergata University, Rome, Italy. Animal experiments were performed according to the Guide for the Care and Use of Laboratory Animals of the National Institutes of Health (NIH Publication No. 85–23, revised 1996). All procedures complied with Italian regulations for laboratory animal care, according to the guidelines and under supervision of the Animal Technology Station, Interdepartmental Service Center, Tor Vergata University, Rome, Italy.

: Not applicable

: The authors declare that they have no competing interests.

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