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Authors
Khan, Kamran A.
Smyth, Michael
Perkins, Gavin D.
Yeung, Joyce
Walker, Alison
McLaren, Rebecca
Fuller, Gordon
Petrou, Stavros
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Funding
Funding for this research was provided by:
National Institute for Health and Care Research Health Technology Assessment Programme (HTA NIHR128086)
National Institute for Health and Care Research Health Technology Assessment Programme (HTA NIHR128086)
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Article History
Received: 27 March 2025
Accepted: 31 December 2025
First Online: 13 January 2026
Declarations
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: Ethics approval for the PACKMAN trial was granted by the West of Scotland Research Ethics Committee (REC number 16/LO/0349) on 01/09/2020. The study was conducted in accordance with the principles of the Declaration of Helsinki and Good Clinical Practice guidelines. Patients were screened by attending paramedics, and verbal assent to participation was obtained prior to randomisation. Written informed consent was subsequently obtained by trained research paramedics, either during the patient’s hospital stay or following discharge from hospital.
: Not applicable.
: The authors declare no competing interests.
