Document is current

Article History

Received: 28 September 2024

Accepted: 29 May 2025

First Online: 1 July 2025

Declarations

:

: The authors declare no competing interests.

: The authors declare no conflicts of interest.

: SJ: Immunofluorescence (IF) staining, in vitro functional assays; real-time PCR, western blot analysis, flow cytometry analysis, RNA-seq library preparation and analysis, ChIP-qPCR, CAM Assay, IHC imaging, Analysis of CT scans, figure design and conception, manuscript preparation and edition, project design and conception, revision and finalization. AB: PEX14 Immunofluorescence staining, in vitro functional assays, flow cytometry analysis. EP: IHC quantification, figure design and conception, project design and conception. DG: Single-cell sequencing analysis. AMN: Western Blots. SK: IHC stainings. WM: Electron Microscopy. CD: Micro-CT scans, FRG: STED Microscopy. L Schüürhuis, LF, L Schridde: Procurement of IHC patient samples. MP, ST: PMP70 IF staining, confocal microscopy, and peroxisome analysis. CB: in vitro functional assays, RNA-seq library preparation and analysis. FAG: Manuscript editing. JG: manuscript conception and edition, FW: project conception, manuscript edition, revision and finalization.

: TCGA patient data and IHC patient CC biopsy material were collected with their consent and approval by the local ethical authorities.