Crossmark

Relevance of a peripheral site of action outside the brain-blood barrier for the beneficial effects of CB2 receptor activation in experimental ALS in male mice

Crossref DOI link: https://doi.org/10.1186/s12964-025-02418-2

Published Online: 2025-10-10

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Gómez-Almería, Marta

Gonzalo-Consuegra, Claudia

Rodríguez-Cueto, Carmen

Cabañas-Cotillas, María

Jiménez-Amor, Alberto

Machín-Díaz, Isabel

Wittwer, Matthias B.

Dzygiel, Pawel

Clemente, Diego

Grether, Uwe

Fernández-Ruiz, Javier https://orcid.org/0000-0002-4490-0604
de Lago, Eva https://orcid.org/0000-0002-6260-3777
Funding

Funding for this research was provided by:

Instituto de Salud Carlos III (CB06/05/0089, CB06/05/0089, CB06/05/0089, PI24/00447, CB06/05/0089, PI21/00302, PI21/00302, CB06/05/0089, CB06/05/0089)

Ministerio de Ciencia e Innovación (RTI-2018-098885-B-100, RTI-2018-098885-B-100, RTI-2018-098885-B-100, PID2021-128906OB-I00, RTI-2018-098885-B-100, RTI-2018-098885-B-100)
License Information

Text and Data Mining valid from 2025-10-10

Version of Record valid from 2025-10-10
More Information

Article History

Received: 27 January 2025

Accepted: 24 August 2025

First Online: 10 October 2025

Declarations

:

: All experiments were carried out in laboratory animals and were conducted according to local and European rules (directive 2010/63/EU) following the ARRIVE guidelines. All animal experiments were approved by the ethical committees of our university and the regulatory institution (PROEX 201.8/22).

: Not applicable.

: The authors declare no competing interests.

Document is current

Any future updates will be listed below