Sill, Sebastian
Ouwens, D. Margriet
Zivehe, Fariba
Hartwig, Sonja
Lehr, Stefan
Bönhof, Gidon J.
Roden, Michael
Al-Hasani, Hadi
Chadt, Alexandra
Strom, Alexander
Funding for this research was provided by:
Universitätsklinikum Düsseldorf. Anstalt öffentlichen Rechts
Article History
Received: 8 October 2025
Accepted: 10 January 2026
First Online: 21 January 2026
Declarations
:
: All animal experiments were complied with the ARRIVE guidelines and were carried out in accordance with the ethical guidelines, the European Council Directive (2010/63/EU), and in accordance with the German Animal Welfare Act and approved by the Ethics Committee of the State Agency for Nature, Environment and Consumer Protection (LANUV, North Rhine-Westphalia, Germany; Reference number: 84-02.04.2022.A006). This study was carried out according to the principles of the 3Rs (Replacement, Reduction and Refinement) to minimize animal suffering and to reduce the number of animals used.
: All authors have approved the manuscript and agree with its submission.
: The authors declare no competing interests.