Miteva, Mariya Timotey https://orcid.org/0000-0002-9558-3047
Protto, Virginia https://orcid.org/0000-0003-1723-405X
Zanzi, Francesco https://orcid.org/0009-0000-8187-9747
Pastore, Francesco https://orcid.org/0000-0003-0064-1505
Simone, Chiara https://orcid.org/0009-0009-3707-4664
Ripoli, Cristian https://orcid.org/0000-0002-5315-0163
Marcocci, Maria Elena https://orcid.org/0000-0003-4751-4263
Piacentini, Roberto https://orcid.org/0000-0003-4215-1643
Grassi, Claudio https://orcid.org/0000-0001-7253-1685
Palamara, Anna Teresa https://orcid.org/0000-0001-8330-4381
De Chiara, Giovanna https://orcid.org/0000-0002-2219-6097
Funding for this research was provided by:
Ministero dell'Università e della Ricerca (PRIN 2022ZYLB7B)
Ministero dell'Università e della Ricerca (PRIN 2022ZYLB7B)
Article History
Received: 12 September 2025
Accepted: 11 February 2026
First Online: 20 February 2026
Declarations
:
: All the experimental protocols used in the present study complied with the European Guide for the Care and Use of Laboratory Animals and institutional guidelines and with the Italian legislation on animal experimentation (Decreto legislativo n. 26/2014, Direttiva UE 63/2010). Experimental protocols were reviewed by the Animal Welfare Body (Istituto Superiore Sanità and Università Cattolica) and authorized by the Italian Ministry of Health (code numbers D9997.N.GRQ and 934/2021-PR).
: Not applicable.
: The authors declare no competing interests.