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Interferon-alpha selectively signals mitochondrial pore opening to allow mitochondrial RNA release in systemic lupus erythematosus: pathophysiological implications

Crossref DOI link: https://doi.org/10.1186/s12964-026-02910-3

Published Online: 2026-05-01

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Huang, Chuan-Yueh

Wu, De-Wei

Hung, Li-Feng

Wu, Chien-Hsiang

Luo, Shue-Fen

Ka, Shuk-Man

Chen, Ann

Ho, Ling-Jun

Lai, Jenn-Haung
Funding

Funding for this research was provided by:

National Health Research Institutes (CS-113-PP-08 and CS-114-PP-08)

Ministry of Science and Technology, Taiwan (NSTC 112-2314-B-400-012-MY2)

Ministry of Science and Technology, Taiwan (NSTC 113-2314-B-182A-059-MY3)

Chang Gung Memorial Hospital, Linkou (CMRPG1P0021)
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Text and Data Mining valid from 2026-05-01

Version of Record valid from 2026-06-18
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Article History

Received: 28 January 2026

Accepted: 25 April 2026

First Online: 1 May 2026

Declarations

:

: The use of human blood samples was approved by the IRB (no. 201509825A3) of Chang Gung Memorial Hospital, Linko, Taiwan. This study was performed in accordance with the Declaration of Helsinki.

: The authors declare no competing interests.

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