Crossmark

Co-targeting EGFR and SUCLG2 disrupts a nuclear transcriptional program driving neuroendocrine differentiation and TKI resistance in castration-resistant prostate cancer

Crossref DOI link: https://doi.org/10.1186/s12964-026-02977-y

Published Online: 2026-06-08

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Chen, Wei-Yu

Huang, Kuan-Hua

Kajla, Gagan

Wen, Yu-Ching

Liu, Ming-Kun

Fan, Yu Ching

Dung, Phan Vu Thuy

Yeh, Hsiu-Lien

Chen, Wei-Hao

Jiang, Kuo-Ching

Li, Han-Ru

Chen, Cheng-Sheng

Huang, Jiaoti

Beltran, Himisha

Liu, Yen-Nien
Funding

Funding for this research was provided by:

National Science and Technology Council, Taiwan (NSTC112-2314-B-038-054-MY3)

National Science and Technology Council, Taiwan (NSTC114-2314-B-038-116-MY3)

National Science and Technology Council, Taiwan (NSTC112-2314-B-038-126-MY3)

Chi Mei Medical Center, Taiwan (112CM-TMU-02)

National Health Research Institutes, Taiwan (NHRI-EX115-11414BI)
License Information

Text and Data Mining valid from 2026-06-08

Version of Record valid from 2026-09-04
More Information

Article History

Received: 20 February 2026

Accepted: 29 May 2026

First Online: 8 June 2026

Declarations

Competing interests: The authors declare no competing interests.

Document is current

Any future updates will be listed below