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Conformational changes in myeloperoxidase induced by ubiquitin and NETs containing free ISG15 from systemic lupus erythematosus patients promote a pro-inflammatory cytokine response in CD4+ T cells

Crossref DOI link: https://doi.org/10.1186/s12967-020-02604-5

Published Online: 2020-11-11

Published Print: 2020-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Carrillo-Vázquez, Daniel Alberto

Jardón-Valadez, Eduardo

Torres-Ruiz, Jiram

Juárez-Vega, Guillermo

Maravillas-Montero, José Luis

Meza-Sánchez, David Eduardo

Domínguez-López, María Lilia

Varela, Jorge Carlos Alcocer

Gómez-Martín, Diana https://orcid.org/0000-0002-1807-0045
Funding

Funding for this research was provided by:

Consejo Nacional de Ciencia y Tecnología (255941)
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Article History

Received: 16 July 2020

Accepted: 5 November 2020

First Online: 11 November 2020

Ethics approval and consent to participate

: All healthy controls and SLE patients signed an informed consent before inclusion, and the protocol was approved by our Institutional Ethics Committee (Ref. 2152) in compliance with the Helsinki declaration.

: The images and data contained in this manuscript are not related to a single individual and are entirely unidentifiable.

: The authors declare that they have no competing interests.

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