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Authors
Mai, Elaine
Chan, Joyce
Goon, Levina
Ego, Braeden K.
Bevers, Jack
Wong, Tiffany
Wong, Manda
Corpuz, Racquel
Xi, Hongkang
Wu, Jia
Schneider, Kellen
Seshasayee, Dhaya
Grimbaldeston, Michele
Nakamura, Gerald
Indjeian, Vahan B.
van Lookeren Campagne, Menno
Loyet, Kelly M.
Comps-Agrar, Laetitia https://orcid.org/0000-0002-5260-6536
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Funding
Funding for this research was provided by:
Genentech
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Article History
Received: 15 September 2021
Accepted: 8 December 2021
First Online: 20 December 2021
Declarations
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: Human tissues from the Lions Eye Institute were recovered in accordance with Food and Drug Administration (FDA) regulations and the ethical codes of conduct of the Eye Bank Association of America (EBAA) regarding utilization of human tissue for research. Written/recorded informed consent was obtained for all donors in accordance with the guidelines from the FDA, EBAA, and the Declaration of Helsinki for research involving the use of human tissue. Clinical records were obtained for all donors and a family questionnaire was obtained when possible.For the samples collected by Genentech Healthy Services, all participants reviewed and consented to Informed Consent Forms which were reviewed and approved by local Institutional Review Board or Ethics Committees for use of clinical data and biomarker analysis.The samples obtained from BioIVT were remnant and therefore the consent was waived. The sample collection protocol was reviewed and approved by the Independent Institutional Review Board (IRB), Inc.
: Not applicable.
: All authors were employees of Genentech, Inc./Hoffmann La-Roche at the time of this study. MvLC and LG are currently employees of Amgen Inc. and Exelixis, respectively.
