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Inhibition of autophagy by chloroquine prevents resistance to PI3K/AKT inhibitors and potentiates their antitumor effect in combination with paclitaxel in triple negative breast cancer models

Crossref DOI link: https://doi.org/10.1186/s12967-022-03462-z

Published Online: 2022-06-27

Published Print: 2022-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Cocco, Stefania

Leone, Alessandra https://orcid.org/0000-0002-1051-2937
Roca, Maria Serena

Lombardi, Rita

Piezzo, Michela

Caputo, Roberta

Ciardiello, Chiara

Costantini, Susan

Bruzzese, Francesca

Sisalli, Maria José

Budillon, Alfredo

De Laurentiis, Michelino
Funding

Funding for this research was provided by:

Ministero della Salute (M3/6)

Regione Campania (POR FESR 2014/2020 – Progetto Campania Onco-Terapie CUP: B61G18000470007)
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Text and Data Mining valid from 2022-06-27

Version of Record valid from 2022-06-27
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Article History

Received: 6 April 2022

Accepted: 25 May 2022

First Online: 27 June 2022

Declarations

:

: The experimental protocols for in vivo mice studies were approved by the Italian Ministry of Health.

: All authors have seen and approved the manuscript and consent publication.

: The authors declare that they have no competing interests.

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