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Comprehensive single-cell transcriptomic and proteomic analysis reveals NK cell exhaustion and unique tumor cell evolutionary trajectory in non-keratinizing nasopharyngeal carcinoma

Crossref DOI link: https://doi.org/10.1186/s12967-023-04112-8

Published Online: 2023-04-25

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Chen, Cuimin

Wang, Chun

Pang, Ruifang

Liu, Huanyu

Yin, Weihua

Chen, Jiakang

Tao, Lili https://orcid.org/0000-0003-4976-4266
Funding

Funding for this research was provided by:

Shenzhen Science and Technology Program (JSGG20201102162802008)

Key clinical research projects of Peking University Shenzhen Hospital (LCYJZD2021007)
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Article History

Received: 16 January 2023

Accepted: 8 April 2023

First Online: 25 April 2023

Declarations

:

: The samples used to perform the proteomic mass spectrometry assays were obtained from patients who gave informed consent and signed an informed consent form. The study was approved by the Ethical Review Committee of Peking University Shenzhen Hospital (PKUSZH) (Approval Number: 2022130), and all experiments were performed in accordance with the Declaration of Helsinki ethical guidelines.

: Not applicable.

: The authors declare that they have no competing interests.

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