Crossmark

High glucose-upregulated PD-L1 expression through RAS signaling-driven downregulation of PTRH1 leads to suppression of T cell cytotoxic function in tumor environment

Crossref DOI link: https://doi.org/10.1186/s12967-023-04302-4

Published Online: 2023-07-11

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Gao, Chenggang

Chen, Jiaoshun

Bai, Jianwei

Zhang, Haoxiang

Tao, Yanyi

Wu, Shihong

Li, Hehe

Wu, Heshui

Shen, Qiang

Yin, Tao
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (81372665, 81772564)
License Information

Text and Data Mining valid from 2023-07-11

Version of Record valid from 2023-07-11
More Information

Article History

Received: 9 December 2022

Accepted: 24 June 2023

First Online: 11 July 2023

Declarations

:

: All experiments involving animals in this research followed the ethical standards set by the Institutional Animal Care and Use Committee of Tongji Medical College, Huazhong University of Science and Technology.

: Not applicable.

: The authors declare that they have no competing interests.

Document is current

Any future updates will be listed below