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An Fgr kinase inhibitor attenuates sepsis-associated encephalopathy by ameliorating mitochondrial dysfunction, oxidative stress, and neuroinflammation via the SIRT1/PGC-1α signaling pathway

Crossref DOI link: https://doi.org/10.1186/s12967-023-04345-7

Published Online: 2023-07-20

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Liu, Yuqiang https://orcid.org/0000-0002-0350-3071
Yang, Han

Luo, Nanbo

Fu, Yifei

Qiu, Fang

Pan, Zhenglong

Li, Xiongjuan

Jian, Wenling

Yang, Xinping

Xue, Qingsheng

Luo, Yan

Yu, Buwei

Liu, Zhiheng
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (82001138)

Science and Technology Planning Project of Shenzhen Municipality (JCYJ20190806164601647)

Science and Technology Planning Project of Shenzhen Municipality (JCYJ20220531092609020)

Sanming Project of Medicine in Shenzhen (SZSM201612026)

Guangdong Basic and Applied Basic Research Foundation (2022A1515111152)
License Information

Text and Data Mining valid from 2023-07-20

Version of Record valid from 2023-07-20
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Article History

Received: 29 March 2023

Accepted: 11 July 2023

First Online: 20 July 2023

Declarations

:

: No human data or tissues were used in this study. The animal study was reviewed and approved by the Committee on the Animal Research Ethics of the Shenzhen Second People’s Hospital.

: Not applicable.

: The authors declare that they have no competing interests.

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