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Circadian rhythm disruption modulates enteric neural precursor cells differentiation leading to gastrointestinal motility dysfunction via the NR1D1/NF-κB axis

Crossref DOI link: https://doi.org/10.1186/s12967-024-05766-8

Published Online: 2024-10-28

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Zhang, Yurui

Xu, Shizhao

Fan, Mengke

Yao, Hailing

Jiang, Chen

He, Qi

Shi, Huiying

Lin, Rong https://orcid.org/0000-0001-6649-8751
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (82100569, 82300616, 81974068, 81770539)

Natural Science Foundation of Hubei Province (2023AFB301)
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Text and Data Mining valid from 2024-10-28

Version of Record valid from 2024-10-28
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Article History

Received: 27 February 2024

Accepted: 15 October 2024

First Online: 28 October 2024

Declarations

:

: All animal studies were authorized by the Animal Care and Use Committee of Union Hospital at Tongji Medical College, Huazhong University of Science and Technology. Approval number: IACUC No. S2803; approval date: 2021.01.06; approved project: Glutamate regulates gliosis of BMSCs to promote ENS regeneration through α-KG and H3K9/H3K27 demethylation.

: All authors state that they have no conflict of interest.

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